Croton macrostachyus. Euphorbiaceae. Hochst. ex Ferret et Galinier. C. macrostachys: A representative tree at. Kakuzi Ranch, Kenya. (Paul K.A. Konuche). Croton macrostachyus Hochst. ex Delile is a species of the genus Croton L., Euphorbiaceae family, commonly known as the spurge family. In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles.
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The methanol leaf extracts showed different degree of mortality against the malaria vector Anopheles arabiensis with LC 50 and LC 90 values of The percent parasitemia and the erythrocytes were counted using crotn white blood cell count method.
Antimalarial Activity of Croton macrostachyus Stem Bark Extracts against Plasmodium berghei In Vivo
Antibacterial activity was demonstrated with minimum inhibitory concentration MIC values ranging from 0. The antibiotic controls amoxicillin, ciprofloxacin, ampicillin, benzylpenicillin, clotrimazole, and cefotaxime showed antimicrobial activity with zones of inhibition within All the extracts had quite equal activity against E.
In tests, sulphate pulping gave a pulp of moderate strength; the wood can be used to make writing paper or newsprint paper after bleaching, but it is unsuitable for the production of wrapping paper.
The seeds also contain several saponins and a resin, which is said to be more toxic to insects than rotenone. Treatment of diabetic mice with doses of the leaf extract resulted in significantly lower levels of fasting blood glucose and the effects of the leaf extract were comparable with the conventional drugs [ 88 ].
Therefore, the present review collates the fragmented information on traditional uses, phytochemistry, pharmacology, and toxicology of the species. Croton macrostachyus tree habit CopyLeft EcoPort. Agricultural Research Reports The weights of all animals were taken before and after the experiment.
Evidence-Based Complementary and Alternative Medicine
Table 4 Chemoprotective assay. In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles, but reports on possible antimicrobial activity of stem bark do not exist.
When testing methanol extracts of C. The column was washed with hexane and toluene and the sample eluted and collected with ethyl acetate. The flowers are heavily scented and give a dark-amber coloured honey with strong flavour. Contrasting results could be attributed to the locality of plant species, parts used, time of collection, storage conditions, and methods of analysis maceostachyus 11 ]. A bark maceration mcarostachyus drunk as an abortifacient and uterotonic, to expel a retained placenta.
Consent to use the experimental animals in the study was obtained from the macrostachyuss committee of the Kenya Medical Research Institute, Center of Biotechnology and Research Development, Department of Malaria.
The methanol extract against E. This article has been cited by other articles in PMC. West is applied on wounds [ 17 ]. Positive antibiotic controls were included in the assays at their recommended effective concentrations. There are book citations related to Croton macrostachyus Hochst.
Chemoprotective Activity The chemoprotective prophylaxis in vivo study was set up and carried out by first treating the animals for four days with the different doses of the studied extracts before exposing them to infection.
Despite the overall favorable development in global malaria incidence and mortality rates, malaria still remains one of the gravest public health threats to human life in many regions. Spices, condiments and medicinal plants in Ethiopia, their taxonomy and agricultural macrosatchyus.
Croton macrostachyus – Useful Tropical Plants
For each solvent extract and each organism, three different experiments were conducted, giving nine readings per extract for each organism. Until recently, malaria used to be the leading cause of death among children in sub-Saharan Africa [ 5 ]. Both extracts significantly inhibited parasitemia, increased survival time, prevented loss of weight and temperature, but did not affect the packed cell volume [ 89 ].
Croton macrostachyus Croton macrostachyus x – 19k – jpg www. These results are in macrostachyue with the previous results by Ziegler et al. BoxNairobi, Kenya. Trotter, and roots of Cyphostemma cyphopetalum Fresen.
A leaf extract is applied against itchy scalp. Studies on the toxicity and therapeutic activity of local taenicidal medications. Volume 2, Families E—I.